STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)    
Predicted Functional Partners:
gap
Glyceraldehyde-3-phosphate dehydrogenase (NADP) (phosphorylating; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.998
tpiA
Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.998
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.995
pgmI
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.989
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.943
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.925
ACL_1395
Ketose bisphosphate aldolase, class-II.
  
 
 0.900
pfk1
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 0.823
hpr2
Phosphotransferase system, phosphocarrier protein; This protein contains one predicted N-terminal transmembrane helix.
  
  
 0.816
ACL_1208
Transcriptional regulator, XRE family.
       0.786
Your Current Organism:
Acholeplasma laidlawii
NCBI taxonomy Id: 441768
Other names: A. laidlawii PG-8A, Acholeplasma laidlawii PG-8A, Acholeplasma laidlawii str. PG-8A, Acholeplasma laidlawii strain PG-8A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.