STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFH70556.1Crotonobetainyl-CoA:carnitine CoA-transferase CaiB; Belongs to the CoA-transferase III family. (401 aa)    
Predicted Functional Partners:
SFH70567.1
hydroxymethylglutaryl-CoA lyase.
  
  0.895
SFH76552.1
Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
    
 0.798
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.679
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
  0.660
SFH87449.1
hydroxymethylglutaryl-CoA lyase.
  
  0.615
SFH70541.1
DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
       0.612
SFI10247.1
Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family.
   
 
  0.608
SFH35167.1
Succinate dehydrogenase subunit B.
     
 0.596
SFH71044.1
glutaryl-CoA dehydrogenase.
 
 0.532
SFH29541.1
Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family.
  
 
 0.493
Your Current Organism:
Halomonas xianhensis
NCBI taxonomy Id: 442341
Other names: CGMCC 1.6848, H. xianhensis, Halomonas sp. A-1, Halomonas xianhensis Zhao et al. 2012, JCM 14849, strain A-1
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