node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GM18_0002 | GM18_0111 | GM18_0002 | GM18_0111 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | 0.985 |
GM18_0002 | GM18_0293 | GM18_0002 | GM18_0293 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: gbm:Gbem_0265 PHP domain protein; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein. | 0.824 |
GM18_0002 | GM18_1927 | GM18_0002 | GM18_1927 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: metallophosphoesterase; KEGG: gbm:Gbem_2302 metallophosphoesterase. | 0.603 |
GM18_0002 | GM18_1928 | GM18_0002 | GM18_1928 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: SMC domain protein; KEGG: gem:GM21_1922 SMC domain protein. | 0.577 |
GM18_0002 | GM18_3876 | GM18_0002 | GM18_3876 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; KEGG: gbm:Gbem_0500 UMUC domain protein DNA-repair protein; PFAM: UMUC domain protein DNA-repair protein. | 0.946 |
GM18_0002 | GM18_4203 | GM18_0002 | GM18_4203 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | SMART: helicase c2; DEAD-like helicase; KEGG: gbm:Gbem_3770 helicase C2. | 0.763 |
GM18_0002 | polA | GM18_0002 | GM18_0443 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.996 |
GM18_0002 | rpoA | GM18_0002 | GM18_0859 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.507 |
GM18_0111 | GM18_0002 | GM18_0111 | GM18_0002 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.985 |
GM18_0111 | GM18_0293 | GM18_0111 | GM18_0293 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | KEGG: gbm:Gbem_0265 PHP domain protein; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein. | 0.960 |
GM18_0111 | GM18_1927 | GM18_0111 | GM18_1927 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | PFAM: metallophosphoesterase; KEGG: gbm:Gbem_2302 metallophosphoesterase. | 0.768 |
GM18_0111 | GM18_1928 | GM18_0111 | GM18_1928 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | PFAM: SMC domain protein; KEGG: gem:GM21_1922 SMC domain protein. | 0.804 |
GM18_0111 | GM18_2365 | GM18_0111 | GM18_2365 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | KEGG: gbm:Gbem_2506 D,D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.850 |
GM18_0111 | GM18_3876 | GM18_0111 | GM18_3876 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | DNA-directed DNA polymerase; KEGG: gbm:Gbem_0500 UMUC domain protein DNA-repair protein; PFAM: UMUC domain protein DNA-repair protein. | 0.733 |
GM18_0111 | GM18_4203 | GM18_0111 | GM18_4203 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | SMART: helicase c2; DEAD-like helicase; KEGG: gbm:Gbem_3770 helicase C2. | 0.736 |
GM18_0111 | ku | GM18_0111 | GM18_0120 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.976 |
GM18_0111 | polA | GM18_0111 | GM18_0443 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.979 |
GM18_0111 | rpoA | GM18_0111 | GM18_0859 | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.698 |
GM18_0293 | GM18_0002 | GM18_0293 | GM18_0002 | KEGG: gbm:Gbem_0265 PHP domain protein; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.824 |
GM18_0293 | GM18_0111 | GM18_0293 | GM18_0111 | KEGG: gbm:Gbem_0265 PHP domain protein; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein. | KEGG: gem:GM21_0109 DNA ligase D; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. | 0.960 |