node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GM18_0439 | ttcA | GM18_0439 | GM18_3738 | KEGG: gbm:Gbem_0361 PP-loop domain protein. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.642 |
GM18_1595 | GM18_1791 | GM18_1595 | GM18_1791 | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: geo:Geob_2117 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: gbm:Gbem_2378 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.923 |
GM18_1595 | ttcA | GM18_1595 | GM18_3738 | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: geo:Geob_2117 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.506 |
GM18_1791 | GM18_1595 | GM18_1791 | GM18_1595 | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: gbm:Gbem_2378 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: geo:Geob_2117 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.923 |
GM18_1791 | ttcA | GM18_1791 | GM18_3738 | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: gbm:Gbem_2378 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.506 |
GM18_2228 | GM18_3701 | GM18_2228 | GM18_3701 | KEGG: gem:GM21_2239 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | KEGG: gem:GM21_0667 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | 0.995 |
GM18_2228 | ttcA | GM18_2228 | GM18_3738 | KEGG: gem:GM21_2239 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.560 |
GM18_3701 | GM18_2228 | GM18_3701 | GM18_2228 | KEGG: gem:GM21_0667 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | KEGG: gem:GM21_2239 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | 0.995 |
GM18_3701 | ttcA | GM18_3701 | GM18_3738 | KEGG: gem:GM21_0667 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.559 |
GM18_3739 | ttcA | GM18_3739 | GM18_3738 | KEGG: gbm:Gbem_0614 nitrite and sulphite reductase 4Fe-4S region; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.618 |
mfd | pth | GM18_0167 | GM18_2633 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.806 |
mfd | ttcA | GM18_0167 | GM18_3738 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.578 |
pth | mfd | GM18_2633 | GM18_0167 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.806 |
pth | ttcA | GM18_2633 | GM18_3738 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.586 |
trmB | truD | GM18_2657 | GM18_2655 | Methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | tRNA pseudouridine synthase D TruD; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.779 |
trmB | ttcA | GM18_2657 | GM18_3738 | Methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.607 |
truD | trmB | GM18_2655 | GM18_2657 | tRNA pseudouridine synthase D TruD; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | Methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.779 |
truD | ttcA | GM18_2655 | GM18_3738 | tRNA pseudouridine synthase D TruD; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.543 |
ttcA | GM18_0439 | GM18_3738 | GM18_0439 | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | KEGG: gbm:Gbem_0361 PP-loop domain protein. | 0.642 |
ttcA | GM18_1595 | GM18_3738 | GM18_1595 | Phosphoadenosine phosphosulfate reductase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: geo:Geob_2117 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.506 |