node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GM21_0961 | argG | GM21_0961 | GM21_3745 | PFAM: aminotransferase class I and II; KEGG: gbm:Gbem_3287 aminotransferase class I and II. | KEGG: gbm:Gbem_3638 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.928 |
GM21_0961 | purA | GM21_0961 | GM21_0565 | PFAM: aminotransferase class I and II; KEGG: gbm:Gbem_3287 aminotransferase class I and II. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.916 |
GM21_1085 | GM21_3742 | GM21_1085 | GM21_3742 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: gbm:Gbem_3178 peptidase M20. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.949 |
GM21_1085 | argB | GM21_1085 | GM21_3740 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: gbm:Gbem_3178 peptidase M20. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.831 |
GM21_1085 | argC | GM21_1085 | GM21_3347 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: gbm:Gbem_3178 peptidase M20. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.869 |
GM21_1085 | argD | GM21_1085 | GM21_3741 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: gbm:Gbem_3178 peptidase M20. | KEGG: gbm:Gbem_3636 acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.940 |
GM21_1085 | argG | GM21_1085 | GM21_3745 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: gbm:Gbem_3178 peptidase M20. | KEGG: gbm:Gbem_3638 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.986 |
GM21_1085 | argH | GM21_1085 | GM21_3748 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: gbm:Gbem_3178 peptidase M20. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: gbm:Gbem_3641 argininosuccinate lyase. | 0.678 |
GM21_3742 | GM21_1085 | GM21_3742 | GM21_1085 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: gbm:Gbem_3178 peptidase M20. | 0.949 |
GM21_3742 | argB | GM21_3742 | GM21_3740 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.977 |
GM21_3742 | argC | GM21_3742 | GM21_3347 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.947 |
GM21_3742 | argD | GM21_3742 | GM21_3741 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | KEGG: gbm:Gbem_3636 acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.981 |
GM21_3742 | argG | GM21_3742 | GM21_3745 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | KEGG: gbm:Gbem_3638 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.999 |
GM21_3742 | argH | GM21_3742 | GM21_3748 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: gbm:Gbem_3641 argininosuccinate lyase. | 0.973 |
GM21_3742 | carA | GM21_3742 | GM21_2310 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: gbm:Gbem_1898 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.992 |
GM21_3742 | carB | GM21_3742 | GM21_2308 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; RimK domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: gbm:Gbem_1900 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.992 |
argB | GM21_1085 | GM21_3740 | GM21_1085 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: gbm:Gbem_3178 peptidase M20. | 0.831 |
argB | GM21_3742 | GM21_3740 | GM21_3742 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.977 |
argB | argC | GM21_3740 | GM21_3347 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
argB | argD | GM21_3740 | GM21_3741 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | KEGG: gbm:Gbem_3636 acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.983 |