node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GM21_0280 | GM21_1052 | GM21_0280 | GM21_1052 | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.905 |
GM21_0280 | GM21_3093 | GM21_0280 | GM21_3093 | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | KEGG: gbm:Gbem_1182 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.911 |
GM21_0280 | folE2 | GM21_0280 | GM21_3787 | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.801 |
GM21_0280 | moaA | GM21_0280 | GM21_1951 | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.810 |
GM21_0280 | moaA-2 | GM21_0280 | GM21_2818 | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.810 |
GM21_0280 | moaA-3 | GM21_0280 | GM21_2931 | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.810 |
GM21_0280 | ribBA | GM21_0280 | GM21_1228 | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.824 |
GM21_0280 | ribBA-2 | GM21_0280 | GM21_2782 | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.824 |
GM21_0622 | folE2 | GM21_0622 | GM21_3787 | KEGG: gbm:Gbem_0608 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.911 |
GM21_0622 | ribBA | GM21_0622 | GM21_1228 | KEGG: gbm:Gbem_0608 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.521 |
GM21_0622 | ribBA-2 | GM21_0622 | GM21_2782 | KEGG: gbm:Gbem_0608 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.521 |
GM21_1052 | GM21_0280 | GM21_1052 | GM21_0280 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: gbm:Gbem_0296 adenylate/guanylate cyclase with CHASE sensor. | 0.905 |
GM21_1052 | GM21_3093 | GM21_1052 | GM21_3093 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | KEGG: gbm:Gbem_1182 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.912 |
GM21_1052 | folE2 | GM21_1052 | GM21_3787 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
GM21_1052 | moaA | GM21_1052 | GM21_1951 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.808 |
GM21_1052 | moaA-2 | GM21_1052 | GM21_2818 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.808 |
GM21_1052 | moaA-3 | GM21_1052 | GM21_2931 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.808 |
GM21_1052 | ribBA | GM21_1052 | GM21_1228 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.848 |
GM21_1052 | ribBA-2 | GM21_1052 | GM21_2782 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.848 |
GM21_2966 | folE2 | GM21_2966 | GM21_3787 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: gbm:Gbem_1317 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.938 |