STRINGSTRING
mshD protein (Clavibacter michiganensis NCPPB382) - STRING interaction network
"mshD" - Mycothiol acetyltransferase in Clavibacter michiganensis NCPPB382
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshDMycothiol acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (306 aa)    
Predicted Functional Partners:
ppkA
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family (727 aa)
            0.921
cysS2
L-cysteine-1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily (426 aa)
 
   
  0.910
mca
Mycothiol S-conjugate amidase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily (293 aa)
 
     
  0.893
glnR
Transcriptional regulator (NP_825219.1| putative GlnR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; Q05943|GLNR_STRCO Transcriptional regulatory protein glnR). InterPro- Transcriptional regulatory protein C terminal pfam00486, Trans_reg_C,Transcriptional regulatory protein, C terminal; Specificity unclear (232 aa)
   
   
  0.887
CMM_2174
Putative fusion protein; conserved hypothetical protein, putative mycothiol biosynthesis + membrane protein (ZP_00057485.1| COG2120- Uncharacterized proteins,LmbE homologs [Thermobifida fusca]; NP_824314.1| hypothetical protein SAV3138 [Streptomyces avermitilis MA-4680]; YP_062519.1| hypothetical protein Lxx16250 [Leifsonia xyli subsp. xyli str. CTCB07]). pfam02585,DUF158, Uncharacterised LmbE-like protein, COG2120. pfam01284, MARVEL, Membrane-associating domain; Function unclear (430 aa)
 
     
  0.869
CMM_1458
Conserved hypothetical protein (ZP_00225908.1| hypothetical protein Krad06004249 [Kineococcus radiotolerans SRS30216]; CAA16043.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). weak similarity to- COG3917, NahD, 2-hydroxychromene-2-carboxylate isomerase [Secondary metabolites biosynthesis,transport, and catabolism]; pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure (208 aa)
   
          0.779
CMM_0688
Conserved hypothetical protein (NP_825702.1| hypothetical protein SAV4525 [Streptomyces avermitilis MA-4680]; NP_962798.1| hypothetical protein MAP3864 [Mycobacterium avium subsp. paratuberculosis str. k10]) (158 aa)
 
          0.740
CMM_2955
Putative glycosyl transferase (NP_789728.1| putative glycosyltransferase [Tropheryma whipplei TW08/27]; ZP_00058815.1| COG0438- Glycosyltransferase [Thermobifida fusca]). , pfam00534, Glycos_transf_1,Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates,including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars. InterPro- Glycosyl transferases group 1; Function unclear (408 aa)
   
 
  0.730
CMM_2498
Putative aminomethyltransferase (ZP_00198226.1| COG0354- Predicted aminomethyltransferase related to GcvT [Kineococcus radiotolerans SRS30216]; NP_825205.1| hypothetical protein SAV4028 [Streptomyces avermitilis MA-4680]). InterPro- Glycine cleavage T-protein (aminomethyl transferase). gcvT- glycine cleavage system T protein. pfam01571, GCV_T, Glycine cleavage T-protein (aminomethyl transferase); Function unclear (384 aa)
 
          0.690
CMM_1562
Conserved hypothetical protein (NP_824345.1| hypothetical protein SAV3169 [Streptomyces avermitilis MA-4680]; ZP_00292803.1| hypothetical protein Tfus02001595 [Thermobifida fusca]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily (137 aa)
 
          0.658
Your Current Organism:
Clavibacter michiganensis NCPPB382
NCBI taxonomy Id: 443906
Other names: C. michiganensis subsp. michiganensis NCPPB 382, Clavibacter michiganensis NCPPB382, Clavibacter michiganensis subsp. michiganensis NCPPB 382, Clavibacter michiganensis subsp. michiganensis str. NCPPB 382, Clavibacter michiganensis subsp. michiganensis strain NCPPB 382
Server load: low (10%) [HD]