STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (176 aa)    
Predicted Functional Partners:
Tneu_0651
PFAM: nucleoside diphosphate kinase; KEGG: pis:Pisl_1626 nucleoside-diphosphate kinase.
  
 
 0.936
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.936
Tneu_1020
PFAM: NUDIX hydrolase; KEGG: pis:Pisl_0088 NUDIX hydrolase.
   
  0.913
Tneu_1993
PFAM: NUDIX hydrolase; KEGG: pis:Pisl_0673 NUDIX hydrolase.
   
  0.913
Tneu_0378
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: pis:Pisl_0226 anaerobic ribonucleoside triphosphate reductase.
    
 0.910
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.751
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.728
Tneu_0477
dTDP-4-dehydrorhamnose reductase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ape:APE_1179.1 dTDP-4-dehydrorhamnose reductase.
   
    0.709
Tneu_1292
KEGG: pis:Pisl_1826 hypothetical protein.
       0.560
tmk
dTMP kinase; PFAM: thymidylate kinase; KEGG: pis:Pisl_1194 dTMP kinase.
  
  
 0.548
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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