STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tneu_1879PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; KEGG: pis:Pisl_1412 peptidase S1 and S6, chymotrypsin/Hap. (289 aa)    
Predicted Functional Partners:
Tneu_1283
KEGG: pis:Pisl_1835 hypothetical protein.
   
 0.810
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.761
Tneu_1543
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pis:Pisl_0554 acetolactate synthase, large subunit, biosynthetic type.
 
  
 0.715
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.713
rpl40e
PFAM: Ribosomal protein L40e; KEGG: pis:Pisl_0479 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
  0.689
Tneu_1159
SMART: WD-40 repeat protein.
  
 
  0.679
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
 0.652
Tneu_1468
PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: pis:Pisl_1034 threonyl/alanyl tRNA synthetase, SAD.
  
 
 0.652
psmB1
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
    
 0.651
psmB2
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
    
 0.651
Your Current Organism:
Pyrobaculum neutrophilum
NCBI taxonomy Id: 444157
Other names: P. neutrophilum V24Sta, Pyrobaculum neutrophilum JCM 9278, Pyrobaculum neutrophilum V24Sta, Pyrobaculum neutrophilum str. V24Sta, Pyrobaculum neutrophilum strain V24Sta, Thermoproteus neutrophilus V24Sta
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