node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABX01517.1 | tgtA | MmarC6_0700 | MmarC6_0282 | PFAM: CoA-binding domain protein; KEGG: mvn:Mevan_1266 CoA-binding domain protein. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.777 |
ABX01618.1 | ABX02111.1 | MmarC6_0801 | MmarC6_1298 | PFAM: putative RNA methylase; THUMP domain protein; KEGG: mvn:Mevan_1154 putative RNA methylase. | PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: mvn:Mevan_0685 tRNA methyltransferase complex GCD14 subunit. | 0.647 |
ABX01618.1 | tgtA | MmarC6_0801 | MmarC6_0282 | PFAM: putative RNA methylase; THUMP domain protein; KEGG: mvn:Mevan_1154 putative RNA methylase. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.758 |
ABX01889.1 | tgtA | MmarC6_1075 | MmarC6_0282 | PFAM: PUA domain containing protein; KEGG: mvn:Mevan_0907 PUA domain containing protein. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.893 |
ABX02111.1 | ABX01618.1 | MmarC6_1298 | MmarC6_0801 | PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: mvn:Mevan_0685 tRNA methyltransferase complex GCD14 subunit. | PFAM: putative RNA methylase; THUMP domain protein; KEGG: mvn:Mevan_1154 putative RNA methylase. | 0.647 |
ABX02111.1 | tgtA | MmarC6_1298 | MmarC6_0282 | PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: mvn:Mevan_0685 tRNA methyltransferase complex GCD14 subunit. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.815 |
ABX02111.1 | truB | MmarC6_1298 | MmarC6_0985 | PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: mvn:Mevan_0685 tRNA methyltransferase complex GCD14 subunit. | rRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.605 |
ABX02236.1 | queC | MmarC6_1423 | MmarC6_0729 | KEGG: mvn:Mevan_0564 6-pyruvoyl tetrahydropterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.983 |
ABX02236.1 | queE | MmarC6_1423 | MmarC6_0871 | KEGG: mvn:Mevan_0564 6-pyruvoyl tetrahydropterin synthase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
ABX02236.1 | tgtA | MmarC6_1423 | MmarC6_0282 | KEGG: mvn:Mevan_0564 6-pyruvoyl tetrahydropterin synthase. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.789 |
nac | tgtA | MmarC6_0663 | MmarC6_0282 | alpha-NAC related protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.702 |
pth | tgtA | MmarC6_0283 | MmarC6_0282 | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.816 |
queC | ABX02236.1 | MmarC6_0729 | MmarC6_1423 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | KEGG: mvn:Mevan_0564 6-pyruvoyl tetrahydropterin synthase. | 0.983 |
queC | queE | MmarC6_0729 | MmarC6_0871 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
queC | tgtA | MmarC6_0729 | MmarC6_0282 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.832 |
queE | ABX02236.1 | MmarC6_0871 | MmarC6_1423 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | KEGG: mvn:Mevan_0564 6-pyruvoyl tetrahydropterin synthase. | 0.998 |
queE | queC | MmarC6_0871 | MmarC6_0729 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.999 |
queE | tgtA | MmarC6_0871 | MmarC6_0282 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.831 |
tgtA | ABX01517.1 | MmarC6_0282 | MmarC6_0700 | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | PFAM: CoA-binding domain protein; KEGG: mvn:Mevan_1266 CoA-binding domain protein. | 0.777 |
tgtA | ABX01618.1 | MmarC6_0282 | MmarC6_0801 | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | PFAM: putative RNA methylase; THUMP domain protein; KEGG: mvn:Mevan_1154 putative RNA methylase. | 0.758 |