STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABX01177.1KEGG: mvn:Mevan_1691 DNA-(apurinic or apyrimidinic site) lyase; PFAM: helix-hairpin-helix motif; protein of unknown function DUF123; HhH-GPD family protein; SMART: Excinuclease ABC C subunit domain protein. (356 aa)    
Predicted Functional Partners:
ABX02459.1
KEGG: mvn:Mevan_0339 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
 
 0.997
ABX01809.1
PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2; KEGG: mvn:Mevan_0978 xylose isomerase domain protein TIM barrel.
  
 
 0.936
fen
XPG I domain protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...]
  
 
 0.876
ABX02535.1
PFAM: CheC domain protein; KEGG: mvn:Mevan_0257 CheC, inhibitor of MCP methylation.
   
   0.757
ABX02536.1
PFAM: CheC domain protein; KEGG: mvn:Mevan_0258 CheC, inhibitor of MCP methylation.
   
   0.757
ABX01072.1
KEGG: mvn:Mevan_1559 hypothetical protein.
   
 
 0.752
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
   
 0.751
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.716
ABX01178.1
PFAM: Protein of unknown function CGGC region; KEGG: cbe:Cbei_5051 protein of unknown function CGGC region.
       0.695
ABX01711.1
PFAM: protein of unknown function DUF34; KEGG: mvn:Mevan_1068 protein of unknown function DUF34.
 
   
 0.682
Your Current Organism:
Methanococcus maripaludis C6
NCBI taxonomy Id: 444158
Other names: M. maripaludis C6, Methanococcus maripaludis str. C6, Methanococcus maripaludis strain C6
Server load: high (82%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.