STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (892 aa)    
Predicted Functional Partners:
htpX
PFAM: peptidase M48 Ste24p; KEGG: mvn:Mevan_1386 peptidase M48 Ste24p; Belongs to the peptidase M48B family.
  
    0.974
ABX01329.1
PFAM: GHMP kinase; KEGG: mvn:Mevan_1385 GHMP kinase.
 
    0.964
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
 0.945
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: mvn:Mevan_1575 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.937
ABX01327.1
PFAM: amino acid-binding ACT domain protein; KEGG: mvn:Mevan_1387 amino acid-binding ACT domain protein.
 
    0.936
glyS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly).
  
 
 0.929
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
  
 0.922
ABX01035.1
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Sel1 domain protein repeat-containing protein; Tetratricopeptide domain protein; KEGG: mvn:Mevan_1518 TPR repeat-containing protein.
   
 0.911
ABX01056.1
Hypothetical protein; KEGG: mvn:Mevan_0278 cell surface protein.
   
 0.911
ABX01248.1
Hypothetical protein.
   
 0.911
Your Current Organism:
Methanococcus maripaludis C6
NCBI taxonomy Id: 444158
Other names: M. maripaludis C6, Methanococcus maripaludis str. C6, Methanococcus maripaludis strain C6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.