node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABX02463.1 | ABX02466.1 | MmarC6_1651 | MmarC6_1654 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | 0.999 |
ABX02463.1 | hisA | MmarC6_1651 | MmarC6_0493 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: mvn:Mevan_1405 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.796 |
ABX02463.1 | hisF | MmarC6_1651 | MmarC6_0949 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.806 |
ABX02463.1 | nadK | MmarC6_1651 | MmarC6_1185 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.577 |
ABX02463.1 | trpA | MmarC6_1651 | MmarC6_1657 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.999 |
ABX02463.1 | trpB | MmarC6_1651 | MmarC6_1656 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
ABX02463.1 | trpD | MmarC6_1651 | MmarC6_1652 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
ABX02463.1 | trpE | MmarC6_1651 | MmarC6_1653 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
ABX02463.1 | trpF | MmarC6_1651 | MmarC6_1655 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mvn:Mevan_0329 phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.999 |
ABX02466.1 | ABX02463.1 | MmarC6_1654 | MmarC6_1651 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mvn:Mevan_0333 indole-3-glycerol-phosphate synthase. | 0.999 |
ABX02466.1 | ABX02496.1 | MmarC6_1654 | MmarC6_1684 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mvn:Mevan_0294 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.406 |
ABX02466.1 | hisA | MmarC6_1654 | MmarC6_0493 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: mvn:Mevan_1405 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.501 |
ABX02466.1 | hisF | MmarC6_1654 | MmarC6_0949 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.584 |
ABX02466.1 | nadK | MmarC6_1654 | MmarC6_1185 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.475 |
ABX02466.1 | trpA | MmarC6_1654 | MmarC6_1657 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.996 |
ABX02466.1 | trpB | MmarC6_1654 | MmarC6_1656 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.997 |
ABX02466.1 | trpD | MmarC6_1654 | MmarC6_1652 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
ABX02466.1 | trpE | MmarC6_1654 | MmarC6_1653 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
ABX02466.1 | trpF | MmarC6_1654 | MmarC6_1655 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mvn:Mevan_0329 phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.997 |
ABX02496.1 | ABX02466.1 | MmarC6_1684 | MmarC6_1654 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mvn:Mevan_0294 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 glutamine amidotransferase of anthranilate synthase. | 0.406 |