STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_0044TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: ppw:PputW619_2676 choline/carnitine/betaine transporter; Belongs to the BCCT transporter (TC 2.A.15) family. (610 aa)    
Predicted Functional Partners:
Amir_0043
Hypothetical protein; KEGG: bxe:Bxe_B0776 putative membrane glycoprotein.
       0.547
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.502
Amir_0040
PFAM: copper resistance D domain protein; KEGG: bja:bll4878 copper export protein.
       0.498
Amir_0041
PFAM: copper resistance protein CopC; KEGG: bra:BRADO4155 copper resistance protein.
       0.498
Amir_0042
PFAM: nuclear export factor GLE1; KEGG: sme:SMa1200 hypothetical protein.
       0.498
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
   
  
 0.489
Amir_5693
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
      
 0.483
Amir_0663
PFAM: glucose sorbosone dehydrogenase; KEGG: ppd:Ppro_1990 hypothetical protein.
  
     0.435
Amir_0911
PFAM: phosphate transporter; KEGG: glo:Glov_0587 phosphate transporter.
      
 0.433
Amir_0029
PFAM: NAD-dependent epimerase/dehydratase; KEGG: xca:xccb100_0085 hypothetical protein.
 
     0.431
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.