STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_3121PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: xau:Xaut_2796 cyclic nucleotide-binding protein. (415 aa)    
Predicted Functional Partners:
Amir_3736
Putative PAS/PAC sensor protein; KEGG: met:M446_3626 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
 0.947
Amir_2370
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
 
  
 0.915
Amir_0966
PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sus:Acid_4295 response regulator receiver modulated serine phosphatase.
  
     0.769
Amir_3606
PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sfu:Sfum_2453 serine phosphatase.
  
     0.765
Amir_3852
KEGG: rle:RL0999 putative two-component regulator sensor histidine kinase protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
  
     0.745
Amir_5095
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: sus:Acid_2843 anti-sigma-factor antagonist.
  
   0.627
Amir_5403
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: swi:Swit_1492 anti-sigma-factor antagonist.
  
   0.574
Amir_5091
KEGG: ank:AnaeK_4253 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein.
  
  
 0.563
Amir_6472
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: swi:Swit_0717 FO synthase.
   
    0.549
Amir_5361
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: dvm:DvMF_0253 putative signal transduction histidine kinase.
 
   0.545
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.