STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_3580PFAM: Lantibiotic dehydratase domain protein; KEGG: scl:sce2385 hypothetical protein. (773 aa)    
Predicted Functional Partners:
Amir_4604
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Beta- ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; condensation domain protein; Acyl transferase; KR domain protein; Alcohol dehydrogenase zinc-binding domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pae:PA3327 non-ribosomal peptide synthetase.
  
  
 0.883
Amir_3892
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; condensation domain protein; KR domain protein; Thioesterase; phosphopantetheine-binding; KEGG: pen:PSEEN2718 polyketide synthase (terminal component).
  
  
 0.846
Amir_3581
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_1089 putative non-ribosomal peptide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
    0.829
Amir_3582
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aav:Aave_3217 pyridoxal-5'-phosphate- dependent enzyme, beta subunit.
       0.773
Amir_3680
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4414 non-ribosomal peptide synthase.
  
  
 0.751
Amir_3577
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3618 non-ribosomal peptide synthetase.
  
  
 0.728
Amir_3579
PFAM: MbtH domain protein; KEGG: scl:sce3255 hypothetical protein.
  
  
 0.720
Amir_3679
PFAM: condensation domain protein; phosphopantetheine-binding; KEGG: peptide synthetase.
 
  
 0.705
Amir_3602
Cyclic nucleotide-binding protein; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Methyltransferase type 11; Methyltransferase type 12; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: smd:Smed_6472 amino acid adenylation domain.
  
  
 0.613
Amir_3294
PFAM: Acyl transferase; AMP-dependent synthetase and ligase; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; KR domain protein; Alcohol dehydrogenase zinc-binding domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I.
  
  
 0.588
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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