STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_4505PFAM: condensation domain protein; KEGG: mxa:MXAN_4415 non-ribosomal peptide synthetase/polyketide synthase. (427 aa)    
Predicted Functional Partners:
Amir_4506
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: mxa:MXAN_3779 non-ribosomal peptide synthetase/polyketide synthase.
   0.995
Amir_3682
PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3631 polyketide synthase type I.
 
 0.985
Amir_4911
PFAM: Beta-ketoacyl synthase; KR domain protein; Acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_3620 polyketide synthase type I.
 
 0.985
Amir_2683
PFAM: Acyl transferase; Beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; Erythronolide synthase docking; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding; KEGG: mxa:MXAN_4527 polyketide synthase.
 
 0.984
Amir_4503
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: aav:Aave_3731 amino acid adenylation domain.
     0.983
Amir_4495
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: mxa:MXAN_4601 non-ribosomal peptide synthase.
     0.982
Amir_2492
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: eca:ECA1488 non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
   0.979
Amir_4853
PFAM: Acyl transferase; Beta-ketoacyl synthase; KR domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: mxa:MXAN_4528 polyketide synthase.
 
   0.978
Amir_2689
PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_0131 amino acid adenylation domain- containing protein.
 
   0.976
Amir_2901
PFAM: AMP-dependent synthetase and ligase; KEGG: pen:PSEEN2716 non-ribosomal peptide synthetase.
 
     0.976
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
Server load: low (16%) [HD]