STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_5077PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: smt:Smal_1176 lysine exporter protein (LysE/YggA). (195 aa)    
Predicted Functional Partners:
Amir_5075
TIGRFAM: transcriptional regulator, ArgP family; PFAM: regulatory protein LysR; KEGG: bav:BAV0190 lysine export transcriptional regulator.
 
   
 0.925
Amir_5078
PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_1010 bifunctional deaminase- reductase-like.
     
 0.513
Amir_3145
PFAM: B3/4 domain protein; KEGG: hypothetical protein.
  
    0.511
Amir_5076
Hypothetical protein.
       0.494
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
      
 0.461
Amir_1784
Cobaltochelatase, CobN subunit; KEGG: pag:PLES_21191 cobalamin biosynthetic protein CobN; TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase.
      
 0.461
Amir_0372
PFAM: protein of unknown function DUF1212; KEGG: rpt:Rpal_1546 protein of unknown function DUF1212.
      
 0.453
Amir_0911
PFAM: phosphate transporter; KEGG: glo:Glov_0587 phosphate transporter.
      
 0.453
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
      
 0.453
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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