STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amir_6649Diguanylate cyclase/phosphodiesterase with GAF sensor; KEGG: xac:XAC2711 phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein. (871 aa)    
Predicted Functional Partners:
Amir_2370
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
 
 0.994
Amir_3736
Putative PAS/PAC sensor protein; KEGG: met:M446_3626 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
  
 
 0.990
Amir_3954
Multi-sensor signal transduction histidine kinase; KEGG: cti:RALTA_B0128 putative multi-site sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein.
 
 
 0.952
Amir_5091
KEGG: ank:AnaeK_4253 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein.
  
 
 0.942
Amir_1661
PFAM: MHYT domain protein; KEGG: sde:Sde_0524 putative integral membrane sensor protein.
    
 0.912
Amir_2209
PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; KEGG: amc:MADE_03205 histidine kinase response regulator hybrid protein.
 
 
  
 0.879
Amir_6278
KEGG: tbd:Tbd_1456 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
0.877
Amir_3741
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; KEGG: mch:Mchl_3342 putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
 
 0.842
Amir_6813
KEGG: rfr:Rfer_4028 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
  
 0.824
Amir_7048
Diguanylate cyclase; KEGG: pen:PSEEN1648 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
  
 0.819
Your Current Organism:
Actinosynnema mirum
NCBI taxonomy Id: 446462
Other names: A. mirum DSM 43827, Actinosynnema mirum DSM 43827, Actinosynnema mirum str. DSM 43827, Actinosynnema mirum strain DSM 43827
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