STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (330 aa)    
Predicted Functional Partners:
Cfla_0995
TIGRFAM: citrate synthase I; KEGG: jde:Jden_0803 citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.992
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.980
Cfla_2803
Malate dehydrogenase (oxaloacetate- decarboxylating); KEGG: sma:SAV_5126 malate oxidoreductase; PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein.
  
 0.967
mqo
TIGRFAM: malate/quinone oxidoreductase; KEGG: bcv:Bcav_0816 malate/quinone oxidoreductase; PFAM: Malate:quinone-oxidoreductase.
    
 0.949
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
    
 0.948
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.926
Cfla_0074
TIGRFAM: malate synthase A; KEGG: aau:AAur_0721 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
   
 0.923
Cfla_1982
KEGG: bcv:Bcav_2217 glutamate synthase (ferredoxin); PFAM: glutamate synthase; ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein.
  
 
 0.919
Cfla_2679
PFAM: aminotransferase class I and II; KEGG: bcv:Bcav_3164 aminotransferase class I and II.
  
 0.914
Cfla_2528
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: jde:Jden_0685 isocitrate dehydrogenase, NADP- dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.900
Your Current Organism:
Cellulomonas flavigena
NCBI taxonomy Id: 446466
Other names: C. flavigena DSM 20109, Cellulomonas flavigena DSM 20109, Cellulomonas flavigena str. DSM 20109, Cellulomonas flavigena strain DSM 20109
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