STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshCcysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (407 aa)    
Predicted Functional Partners:
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
  
 0.923
mca
Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
  
 0.861
mshB
1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranosidedeacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
 
 
 0.842
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.763
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
      
 0.729
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR005121:IPR005146:IPR002547:IPR005147:IPR 004532:IPR020825:IPR012340:IPR016027:IPR009061; KEGG: tfu:Tfu_2060 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; tRNA synthetase B5; t-RNA-binding domain protein; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; SMART: B3/4 domain protein; ferredoxin-fold anticodon-binding; tRNA synthetase B5; SPTR: C1YVE0 Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B [...]
  
  
 0.683
thrS
COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR012947:IPR002314:IPR004154:IPR006195:IPR 018158:IPR018163:IPR002320; KEGG: tfu:Tfu_2108 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; Anticodon-binding domain protein; SPTR: C1YSN0 Ser-tRNA(Thr) hydrolase; threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II a [...]
 
  
 0.678
Ndas_3143
Protein of unknown function DUF901; InterPro IPR010298; KEGG: tfu:Tfu_1028 hypothetical protein; PFAM: protein of unknown function DUF901; SPTR: C1YUT2 Predicted RNA-binding protein containing a PIN domain; PFAM: Protein of unknown function (DUF901).
  
    0.674
Ndas_3412
InterPro IPR012336; KEGG: tfu:Tfu_2203 hypothetical protein; SPTR: C1YQC3 Putative uncharacterized protein; PFAM: DSBA-like thioredoxin domain.
  
  
 0.642
Ndas_5268
InterPro IPR001173; KEGG: tfu:Tfu_3054 glycosyltransferase involved in cell wall biogenesis; PFAM: glycosyl transferase family 2; SPTR: C1YS97 Glycosyl transferase; PFAM: Glycosyl transferase family 2.
      
 0.629
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
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