STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndas_3698Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674; KEGG: tfu:Tfu_0551 putative lipoprotein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: C1YU37 HD-GYP domain-containing protein; PFAM: HD domain. (445 aa)    
Predicted Functional Partners:
Ndas_3699
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: tfu:Tfu_0550 metal-dependent phosphohydrolase, HD region; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1YU36 Uncharacterized domain HDIG-containing protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
  
0.888
Ndas_5202
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR009082:IPR003660:IPR001789:IPR003594:IPR 003661:IPR005467:IPR011006:IPR003018:IPR004358; KEGG: tfu:Tfu_0286 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase HAMP region domain protein; histidine kinase A domain protein; GAF domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain pro [...]
  
 
 0.832
Ndas_0170
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000160:IPR000014:IPR001633:IPR001610:IPR 013655; KEGG: tfu:Tfu_0610 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: C1YHV9 PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein; TIGRFAM: diguanylate [...]
 
 
 0.796
Ndas_4611
Protein of unknown function DUF88; InterPro IPR002790; KEGG: tfu:Tfu_3005 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: C1YGL0 Uncharacterized conserved protein; PFAM: Protein of unknown function DUF88.
  
     0.663
Ndas_0080
KEGG: sro:Sros_8571 hypothetical protein; SPTR: C1YHY6 Putative uncharacterized protein.
  
     0.653
Ndas_2882
KEGG: tfu:Tfu_1937 hypothetical protein; SPTR: C1YJW4 Putative uncharacterized protein.
  
     0.651
Ndas_5006
KEGG: tfu:Tfu_2706 hypothetical protein; SPTR: C1YIF8 Putative uncharacterized protein.
  
     0.650
Ndas_3799
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR016040:IPR001509:IPR002347; KEGG: tfu:Tfu_0537 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: C1YL54 Nucleoside-diphosphate-sugar epimerase; PFAM: NAD dependent epimerase/dehydratase family.
  
     0.623
Ndas_4368
Bifunctional DNA primase/polymerase; InterPro IPR015330; KEGG: tfu:Tfu_2729 hypothetical protein; PFAM: Bifunctional DNA primase/polymerase; SPTR: C1YGP2 Bifunctional DNA primase/polymerase famiily protein; PFAM: Bifunctional DNA primase/polymerase, N-terminal.
  
     0.611
Ndas_0136
KEGG: tfu:Tfu_0475 hypothetical protein; SPTR: C1YHJ6 Putative uncharacterized protein.
  
     0.597
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
Server load: medium (48%) [HD]