STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndas_4945Peptidase S1 and S6 chymotrypsin/Hap; InterPro IPR001254:IPR001314:IPR018114:IPR009003; KEGG: sco:SCO4985 hypothetical protein; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; SPTR: C1YIL8 Secreted trypsin-like serine protease; PFAM: Trypsin. (514 aa)    
Predicted Functional Partners:
Ndas_4943
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR004358:IPR003594:IPR 009082:IPR003661; KEGG: xce:Xcel_1425 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: C1YIM0 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
       0.507
Ndas_4944
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR001789:IPR011991:IPR011006; KEGG: lxx:Lxx22010 two-component system, regulatory protein; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; transcriptional regulator domain protein; SPTR: C1YIL9 Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain; PFAM: Response regulator receiver domain; Transcr [...]
       0.507
Ndas_4142
YD repeat protein; COGs: COG3209 Rhs family protein; InterPro IPR006530; KEGG: sco:SCO0072 secreted protein; PFAM: YD repeat-containing protein; SPTR: C1YG46 Rhs family protein; TIGRFAM: YD repeat protein; PFAM: RHS Repeat; TIGRFAM: YD repeat (two copies).
 
  
 0.417
Ndas_0494
Acyl transferase; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR009081:IPR006162:IPR018201:IPR018294:IPR 016038:IPR001227:IPR016040:IPR016039:IPR016035:IPR011032:I PR016036:IPR014030:IPR014031:IPR014043:IPR006163:IPR013154 :IPR013149:IPR002198; KEGG: sgr:SGR_6179 putative type-I PKS; PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; short-chain dehydrogenase/reductase SDR; SPTR: C1YLQ6 Short chain dehydrogenase/beta-ketoacyl synthase/zinc- [...]
 
 
 0.402
Your Current Organism:
Nocardiopsis dassonvillei
NCBI taxonomy Id: 446468
Other names: N. dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei str. DSM 43111, Nocardiopsis dassonvillei subsp. dassonvillei strain DSM 43111
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