node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACZ21231.1 | ACZ22462.1 | Sked_12890 | Sked_25580 | PFAM: Thymidine kinase. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.908 |
ACZ21231.1 | ACZ22475.1 | Sked_12890 | Sked_25710 | PFAM: Thymidine kinase. | PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase. | 0.941 |
ACZ21231.1 | ACZ22476.1 | Sked_12890 | Sked_25720 | PFAM: Thymidine kinase. | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric. | 0.935 |
ACZ21231.1 | ACZ23248.1 | Sked_12890 | Sked_33530 | PFAM: Thymidine kinase. | Predicted extracellular nuclease; PFAM: 5'-nucleotidase, C-terminal domain; Endonuclease/Exonuclease/phosphatase family; Calcineurin-like phosphoesterase; TIGRFAM: LPXTG-motif cell wall anchor domain. | 0.908 |
ACZ21231.1 | dut | Sked_12890 | Sked_16120 | PFAM: Thymidine kinase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.980 |
ACZ21231.1 | prfA | Sked_12890 | Sked_09920 | PFAM: Thymidine kinase. | Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.807 |
ACZ21231.1 | pyrG | Sked_12890 | Sked_22080 | PFAM: Thymidine kinase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.577 |
ACZ21231.1 | tadA | Sked_12890 | Sked_04500 | PFAM: Thymidine kinase. | tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.597 |
ACZ21231.1 | thyA | Sked_12890 | Sked_23310 | PFAM: Thymidine kinase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.973 |
ACZ21231.1 | tmk | Sked_12890 | Sked_32590 | PFAM: Thymidine kinase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.939 |
ACZ22462.1 | ACZ21231.1 | Sked_25580 | Sked_12890 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | PFAM: Thymidine kinase. | 0.908 |
ACZ22462.1 | ACZ22475.1 | Sked_25580 | Sked_25710 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase. | 0.970 |
ACZ22462.1 | ACZ22476.1 | Sked_25580 | Sked_25720 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric. | 0.966 |
ACZ22462.1 | ACZ23248.1 | Sked_25580 | Sked_33530 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Predicted extracellular nuclease; PFAM: 5'-nucleotidase, C-terminal domain; Endonuclease/Exonuclease/phosphatase family; Calcineurin-like phosphoesterase; TIGRFAM: LPXTG-motif cell wall anchor domain. | 0.926 |
ACZ22475.1 | ACZ21231.1 | Sked_25710 | Sked_12890 | PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase. | PFAM: Thymidine kinase. | 0.941 |
ACZ22475.1 | ACZ22462.1 | Sked_25710 | Sked_25580 | PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.970 |
ACZ22475.1 | ACZ22476.1 | Sked_25710 | Sked_25720 | PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase. | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric. | 0.998 |
ACZ22475.1 | ACZ23248.1 | Sked_25710 | Sked_33530 | PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase. | Predicted extracellular nuclease; PFAM: 5'-nucleotidase, C-terminal domain; Endonuclease/Exonuclease/phosphatase family; Calcineurin-like phosphoesterase; TIGRFAM: LPXTG-motif cell wall anchor domain. | 0.944 |
ACZ22475.1 | tadA | Sked_25710 | Sked_04500 | PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase. | tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.499 |
ACZ22476.1 | ACZ21231.1 | Sked_25720 | Sked_12890 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric. | PFAM: Thymidine kinase. | 0.935 |