STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adprt3Poly [ADP-ribose] polymerase. (2536 aa)    
Predicted Functional Partners:
ubcC
Ubiquitin-conjugating enzyme protein UbcC; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.891
mvpB
Major vault protein beta; Unknown, though MVP-beta is required for normal vault structure.
    
 
 0.819
mvpA
Major vault protein alpha; Unknown, though MVP-alpha is required for normal vault structure.
    
 
 0.818
PARTf
Poly [ADP-ribose] polymerase.
    
 
 0.729
ParG
Uncharacterized protein.
    
 
 0.671
H4a
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 
 0.467
ku80
X-ray repair cross-complementing protein 5; Involved in non-homologous end joining (NHEJ) DNA double strand break repair.
   
 
 0.416
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.