STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0185382Uncharacterized protein. (514 aa)    
Predicted Functional Partners:
DDB0205063
Uncharacterized protein.
 
  
   0.903
DDB0189735
CS domain-containing protein.
    
 0.869
hspD
Heat shock cognate 90 kDa protein; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity); Belongs to the heat shock protein 90 family.
   
 0.844
trap1
TNF receptor-associated protein 1 homolog, mitochondrial; Chaperone that expresses an ATPase activity.
   
 
 0.702
tstB
TSET complex member tstB.
   
 
 0.701
grp94
Endoplasmin homolog; May play a role in late differentiation as well as in starvation response. When overexpressed, suppresses the ability to form normal fruiting bodies and impairs prespore differentiation as well as maturation into spores; Belongs to the heat shock protein 90 family.
   
 
 0.629
ahsa
Activator of 90 kDa heat shock protein ATPase homolog; Co-chaperone that stimulates hspD/HSP90 ATPase activity.
   
 
 0.446
ttc4
Tetratricopeptide repeat protein 4 homolog; Belongs to the TTC4 family.
   
 
 0.428
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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