Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

cprA

Cysteine proteinase 1; Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation (343 aa)

Predicted Functional Partners:

DDB0229935

0.780

DDB0189094

0.779

grn

0.753

zfaA

0.712

ddj1

0.699

DDB0183824

0.691

DDB0186550

0.689

cyp522A1

0.676

cln5

0.664

cprB

0.655

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: ATCC 11735, D. discoideum, Dictyostelium discoideum, IMI 69094

Export your current network:

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same PNG format, but resolution at 400 dpi

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0183824	DDB0186550	DDB0231824	DDB0233890	annotation not available	annotation not available	0.716
DDB0183824	cln5	DDB0231824	DDB0234077	annotation not available	Ceroid-lipofuscinosis neuronal protein 5 homolog; Belongs to the CLN5 family	0.700
DDB0183824	cprA	DDB0231824	DDB0201647	annotation not available	Cysteine proteinase 1; Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation	0.691
DDB0183824	ddj1	DDB0231824	DDB0215016	annotation not available	Heat shock protein Ddj1	0.714
DDB0183824	grn	DDB0231824	DDB0238428	annotation not available	Granulin; Belongs to the granulin family	0.708
DDB0186550	DDB0183824	DDB0233890	DDB0231824	annotation not available	annotation not available	0.716
DDB0186550	cln5	DDB0233890	DDB0234077	annotation not available	Ceroid-lipofuscinosis neuronal protein 5 homolog; Belongs to the CLN5 family	0.760
DDB0186550	cprA	DDB0233890	DDB0201647	annotation not available	Cysteine proteinase 1; Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation	0.689
DDB0186550	ddj1	DDB0233890	DDB0215016	annotation not available	Heat shock protein Ddj1	0.714
DDB0186550	grn	DDB0233890	DDB0238428	annotation not available	Granulin; Belongs to the granulin family	0.708
DDB0189094	DDB0229935	DDB0189094	DDB0229935	Uncharacterized protein DDB_G0290803	Uncharacterized protein DDB_G0292248	0.693
DDB0189094	cprA	DDB0189094	DDB0201647	Uncharacterized protein DDB_G0290803	Cysteine proteinase 1; Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation	0.779
DDB0189094	cprB	DDB0189094	DDB0214998	Uncharacterized protein DDB_G0290803	Cysteine proteinase 2; Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation	0.520
DDB0189094	cyp522A1	DDB0189094	DDB0233031	Uncharacterized protein DDB_G0290803	Probable cytochrome P450 522A1	0.780
DDB0229935	DDB0189094	DDB0229935	DDB0189094	Uncharacterized protein DDB_G0292248	Uncharacterized protein DDB_G0290803	0.693
DDB0229935	cprA	DDB0229935	DDB0201647	Uncharacterized protein DDB_G0292248	Cysteine proteinase 1; Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation	0.780
DDB0229935	cprB	DDB0229935	DDB0214998	Uncharacterized protein DDB_G0292248	Cysteine proteinase 2; Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation	0.482
DDB0229935	cyp522A1	DDB0229935	DDB0233031	Uncharacterized protein DDB_G0292248	Probable cytochrome P450 522A1	0.631
cln5	DDB0183824	DDB0234077	DDB0231824	Ceroid-lipofuscinosis neuronal protein 5 homolog; Belongs to the CLN5 family	annotation not available	0.700
cln5	DDB0186550	DDB0234077	DDB0233890	Ceroid-lipofuscinosis neuronal protein 5 homolog; Belongs to the CLN5 family	annotation not available	0.760

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