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tkrA protein (Dictyostelium discoideum) - STRING interaction network
"tkrA" - Probable 2-ketogluconate reductase in Dictyostelium discoideum
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
tkrAProbable 2-ketogluconate reductase; Catalyzes the NADPH-dependent reduction of 2,5-diketo-D- gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2-keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA) (334 aa)    
Predicted Functional Partners:
agxt
Serine--pyruvate aminotransferase; Dual metabolic roles of gluconeogenesis and glyoxylate detoxification; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family (407 aa)
 
 
  0.988
DDB0230179
annotation not available (468 aa)
     
  0.972
DDB0186160
annotation not available (303 aa)
   
 
  0.970
haox
Hydroxyacid oxidase; Has 2-hydroxyacid oxidase activity; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family (388 aa)
   
 
  0.962
masB
Malate synthase (542 aa)
     
 
  0.957
masA
Malate synthase (543 aa)
     
 
  0.957
DDB0231437
Probable gluconokinase; Belongs to the gluconokinase GntK/GntV family (200 aa)
   
 
  0.944
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (136 aa)
   
  0.928
sds
L-serine dehydratase; Belongs to the serine/threonine dehydratase family (350 aa)
     
 
  0.817
DDB0230210
annotation not available (1173 aa)
     
 
  0.817
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: ATCC 11735, D. discoideum, Dictyostelium discoideum, IMI 69094
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