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hipA protein (Dictyostelium discoideum) - STRING interaction network
"hipA" - I/LWEQ domain-containing protein in Dictyostelium discoideum
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
hipAI/LWEQ domain-containing protein (960 aa)    
Predicted Functional Partners:
epnA
Epsin; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2) (686 aa)
     
 
  0.966
clc
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family (194 aa)
     
 
  0.963
DDB0218102
ANTH domain-containing protein (695 aa)
     
 
  0.948
chcA
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (1694 aa)
     
 
  0.926
arpB
Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general role in [...] (392 aa)
       
 
  0.869
vilA
Villidin; May function as a linker between membranes and the actin cytoskeleton (1704 aa)
     
   
  0.831
DDB0220465
Actin domain-containing protein; Belongs to the actin family (944 aa)
       
 
  0.807
wasA
Wiscott-Aldrich syndrome protein (399 aa)
     
 
  0.772
DDB0232169
WASP-related protein (583 aa)
     
 
  0.772
mhcA
Myosin-2 heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family (2116 aa)
     
 
  0.766
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: ATCC 11735, D. discoideum, Dictyostelium discoideum, IMI 69094
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