STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB_G0284701Enolase superfamily member DDB_G0284701; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (437 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase.
     
 0.774
DDB_G0283123
PK domain-containing protein.
     
 0.774
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
     
 0.767
mcee
Methylmalonyl-CoA epimerase, mitochondrial; Belongs to the methylmalonyl-CoA epimerase family.
     
 0.767
rbsk
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.764
DDB_G0292440
Uncharacterized sugar kinase; Belongs to the carbohydrate kinase PfkB family.
    
 0.758
adk
Adenosine kinase; ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
    
 0.758
DDB0188240
Uncharacterized protein.
  
 
 0.734
cpox
Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX (By similarity).
   
 
 0.726
DDB0169401
Metalloenzyme domain-containing protein.
   
 
  0.722
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.