STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB_G0292894Uncharacterized cyclodeaminase; Belongs to the ornithine cyclodeaminase/mu-crystallin family. (368 aa)    
Predicted Functional Partners:
prodh
Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate.
  
 
 0.975
pycr1
Pyrroline-5-carboxylate reductase 1; Belongs to the pyrroline-5-carboxylate reductase family.
  
 
 0.947
odc
Probable ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.943
oatA
Probable ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.934
DDB0187236
Proline iminopeptidase; Belongs to the peptidase S33 family.
     
 0.932
DDB0188301
Uncharacterized protein; Belongs to the arginase family.
  
 
 0.928
DDB0202598
Fe2OG dioxygenase domain-containing protein.
     
  0.900
lap
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity). Belongs to the peptidase M17 family.
     
  0.900
argC
N-acetyl-gamma-glutamyl-phosphate reductase; In the C-terminal section; belongs to the NAGSA dehydrogenase family.
  
  
 0.717
cysK
Cysteine synthase.
  
 
 0.675
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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