STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaja1DnaJ homolog subfamily A member 1 homolog; Co-chaperone for Hsp70 family members. Plays a role in protein transport into mitochondria and in the regulation of apoptosis via its role as co-chaperone (By similarity). (459 aa)    
Predicted Functional Partners:
bip1-1
Luminal-binding protein 1; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER; Belongs to the heat shock protein 70 family.
 
 0.898
DDB_G0285709
Heat shock 70-related protein 5; May function in protein folding and assembly, and disassembly of protein complexes.
 
 0.855
DDB_G0293678
Heat shock cognate 70 kDa protein 4; May function in protein folding and assembly, and disassembly of protein complexes.
 
 0.854
hspB
Heat shock cognate 70 kDa protein 1; Affects actin polymerization through interaction with the actin-binding protein CAP32/34 (acpA/acpB). Acts as a chaperone by stimulating the refolding of denaturated acpA and acpB, but neither stimulates nor inhibits the capping activity of native CAP32/34. Belongs to the heat shock protein 70 family.
 
 0.852
DDB_G0293674
Heat shock cognate 70 kDa protein 3; May function in protein folding and assembly, and disassembly of protein complexes.
 
 0.852
hspE-1
Heat shock cognate 70 kDa protein 2; May function in protein folding and assembly, and disassembly of protein complexes.
 
 0.849
ucr
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 
 0.827
ddj1
Heat shock protein.
  
  
 
0.812
Spt6
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
  
  
 0.793
bip2
Luminal-binding protein 2; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER; Belongs to the heat shock protein 70 family.
 
 0.757
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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