STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0188803Nudix hydrolase domain-containing protein. (362 aa)    
Predicted Functional Partners:
DDB_G0269890
NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.
  
 
 0.604
DDB0187387
Uncharacterized protein.
    
 
 0.594
ctps
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.565
DDB0189892
PAT1 domain-containing protein.
    
 
 0.557
pex14
Peroxisomal membrane protein PEX14; May be a component of the peroxisomal translocation machinery; Belongs to the peroxin-14 family.
    
  0.519
pex13
Probable peroxisomal membrane protein PEX13; May be a component of the peroxisomal translocation machinery; Belongs to the peroxin-13 family.
   
 
 0.512
pex5
Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
     
 0.510
pex12
Putative peroxisome assembly protein 12; Required for protein import into peroxisomes; Belongs to the pex2/pex10/pex12 family.
   
 
  0.508
pex10
Peroxisome biogenesis factor 10; Involved in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family.
   
 
  0.501
ubqD
Polyubiquitin-D; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradat [...]
     
  0.499
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.