STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB_G0280565Calponin-homology (CH) domain-containing protein. (842 aa)    
Predicted Functional Partners:
ypel
Protein yippee-like; Belongs to the yippee family.
   
 
  0.450
abpD
Interaptin; May function as linker between cellular membranes and the actin cytoskeleton. Required for normal development of fruiting bodies.
    
 
0.413
abpA
Alpha-actinin A; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Increases the actin-stimulated ATPase activity of myosin. Involved in vegetative cell growth, phagocytosis, motility and development, probably through stabilization of the actin network in the cortical cytoskeleton.
    
 
0.413
DDB0204997
Calponin-homology (CH) domain-containing protein.
    
  0.411
DDB0189688
Calponin-homology (CH) domain-containing protein.
    
  0.411
fba
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
     
 0.411
DDB0217904
Erf4 domain-containing protein.
   
 
  0.408
DDB0189814
Uncharacterized protein.
   
 
  0.405
pgmA
Phosphoglucomutase-1; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family.
   
 
  0.401
pirA
Protein pirA; Involved in regulation of actin and microtubule organization.
    
  0.401
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.