STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0216979F-box domain-containing protein. (447 aa)    
Predicted Functional Partners:
DDB0204007
Uncharacterized protein.
   
  
 0.799
DDB0190214
Uncharacterized protein.
      
 0.798
nfyA
Nuclear transcription factor Y subunit alpha; Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity).
   
  
 0.791
bzpS
Probable basic-leucine zipper transcription factor S; Probable transcriptional regulator; Belongs to the bZIP family.
      
 0.790
mybD
Myb-like protein D.
      
 0.790
cprD
Cysteine proteinase 4.
    
   0.754
TPS6
Terpene synthase.
   
    0.476
DDB0206356
Protein phosphatase; Belongs to the PP2C family.
   
 
 0.471
dhkA
Hybrid signal transduction histidine kinase A; Acts as a receptor histidine kinase for the cytokinin SDF-2 in a signal transduction pathway that regulates prestalk gene expression and controls terminal differentiation of prespore cells. Binding of SDF-2 to this protein inhibits phosphorelay and induces rapid sporulation. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain.
    
 
 0.426
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.