STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0202048Uncharacterized protein. (472 aa)    
Predicted Functional Partners:
tnpo
Transportin; Functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC). Mediates docking of the substrate-importin complex to distinct nucleoporins (By similarity).
   
 
 0.906
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap struct [...]
    
 
 0.842
DDB0203538
RRM domain-containing protein.
   
 
 0.828
DDB0184371
Uncharacterized protein.
    
 
 0.826
DDB_G0275027
RRM domain-containing protein.
    
 
 0.826
Uap56
Uncharacterized protein.
    
 
 0.777
DDB0186472
RRM domain-containing protein.
    
 
 0.715
DDB0186471
RRM domain-containing protein.
    
 
 0.715
DDB0186962
Uncharacterized protein.
   
 
 0.702
DDB0215887
Uncharacterized protein.
   
 
 0.701
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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