STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
washc3WASH complex subunit 3. (354 aa)    
Predicted Functional Partners:
DDB_G0292878
WAS protein family homolog DDB_G0292878; Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization.
    
 0.979
washc5
WASH complex subunit 5.
  
 0.975
washc4
WASH complex subunit 4.
  
 0.968
washc2
WASH complex subunit 2.
   
 0.957
DDB0167979
Uncharacterized protein.
    
 
 0.908
mroh1
Maestro heat-like repeat-containing protein family member 1.
   
 
 0.721
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection.
    
 
 0.501
brk1
Protein BRICK1; Involved in regulation of actin and microtubule organization. Belongs to the BRK1 family.
    
 
 0.443
vps29
Vacuolar protein sorting-associated protein 29; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection.
   
 
 0.422
DDB0216403
Heat shock factor (HSF)-type DNA-binding domain-containing protein.
   
 
 0.409
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.