node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceB | acs | sce8725 | sce7927 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.982 |
aceB | cis1 | sce8725 | sce1738 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Citrate synthase; Family membership; Belongs to the citrate synthase family. | 0.961 |
aceB | cis2 | sce8725 | sce8281 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | 0.961 |
aceB | pepM | sce8725 | sce7305 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Phosphoenolpyruvate mutase; High confidence in function and specificity. | 0.638 |
aceB | sce0442 | sce8725 | sce0442 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Serine-pyruvate aminotransferase; Family membership. | 0.936 |
aceB | sce1736 | sce8725 | sce1736 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Citrate synthase (EC 2.3.3.1). | 0.963 |
acs | aceB | sce7927 | sce8725 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | 0.982 |
acs | cis1 | sce7927 | sce1738 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase; Family membership; Belongs to the citrate synthase family. | 0.983 |
acs | cis2 | sce7927 | sce8281 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | 0.983 |
acs | pepM | sce7927 | sce7305 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Phosphoenolpyruvate mutase; High confidence in function and specificity. | 0.643 |
acs | sce1736 | sce7927 | sce1736 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase (EC 2.3.3.1). | 0.984 |
cis1 | aceB | sce1738 | sce8725 | Citrate synthase; Family membership; Belongs to the citrate synthase family. | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | 0.961 |
cis1 | acs | sce1738 | sce7927 | Citrate synthase; Family membership; Belongs to the citrate synthase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.983 |
cis1 | cis2 | sce1738 | sce8281 | Citrate synthase; Family membership; Belongs to the citrate synthase family. | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | 0.924 |
cis1 | pepM | sce1738 | sce7305 | Citrate synthase; Family membership; Belongs to the citrate synthase family. | Phosphoenolpyruvate mutase; High confidence in function and specificity. | 0.791 |
cis1 | sce1736 | sce1738 | sce1736 | Citrate synthase; Family membership; Belongs to the citrate synthase family. | Citrate synthase (EC 2.3.3.1). | 0.971 |
cis2 | aceB | sce8281 | sce8725 | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | 0.961 |
cis2 | acs | sce8281 | sce7927 | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.983 |
cis2 | cis1 | sce8281 | sce1738 | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | Citrate synthase; Family membership; Belongs to the citrate synthase family. | 0.924 |
cis2 | pepM | sce8281 | sce7305 | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | Phosphoenolpyruvate mutase; High confidence in function and specificity. | 0.791 |