node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PHZ_c1227 | rplD | PHZ_c1227 | PHZ_c1231 | Translation elongation factor EF-Tu. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.980 |
PHZ_c1227 | rplL | PHZ_c1227 | PHZ_c1217 | Translation elongation factor EF-Tu. | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.919 |
PHZ_c1227 | rplM | PHZ_c1227 | PHZ_c1653 | Translation elongation factor EF-Tu. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.970 |
PHZ_c1227 | rplV | PHZ_c1227 | PHZ_c1235 | Translation elongation factor EF-Tu. | 30S ribosomal protein S3; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.980 |
PHZ_c1227 | rpsB | PHZ_c1227 | PHZ_c1780 | Translation elongation factor EF-Tu. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.971 |
PHZ_c1227 | tig | PHZ_c1227 | PHZ_c1700 | Translation elongation factor EF-Tu. | FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.648 |
PHZ_c1227 | tsf | PHZ_c1227 | PHZ_c1779 | Translation elongation factor EF-Tu. | Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.984 |
pyrH | rplM | PHZ_c1778 | PHZ_c1653 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.578 |
pyrH | rplV | PHZ_c1778 | PHZ_c1235 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 30S ribosomal protein S3; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.504 |
pyrH | rpsB | PHZ_c1778 | PHZ_c1780 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.981 |
pyrH | rrf | PHZ_c1778 | PHZ_c1777 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Ribosome recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.997 |
pyrH | tig | PHZ_c1778 | PHZ_c1700 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.800 |
pyrH | tsf | PHZ_c1778 | PHZ_c1779 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.996 |
rplD | PHZ_c1227 | PHZ_c1231 | PHZ_c1227 | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | Translation elongation factor EF-Tu. | 0.980 |
rplD | rplL | PHZ_c1231 | PHZ_c1217 | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.997 |
rplD | rplM | PHZ_c1231 | PHZ_c1653 | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
rplD | rplV | PHZ_c1231 | PHZ_c1235 | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 30S ribosomal protein S3; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.999 |
rplD | rpsB | PHZ_c1231 | PHZ_c1780 | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.999 |
rplD | rrf | PHZ_c1231 | PHZ_c1777 | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | Ribosome recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.974 |
rplD | tig | PHZ_c1231 | PHZ_c1700 | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.978 |