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STRINGSTRING
TOP6B protein (Hordeum vulgare) - STRING interaction network
"TOP6B" - DNA topoisomerase 6 subunit B in Hordeum vulgare
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP6BDNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family (690 aa)    
Predicted Functional Partners:
TOP6A
DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity (441 aa)
 
 
  0.994
MLOC_14192.4
Uncharacterized protein (392 aa)
 
 
  0.976
MLOC_63119.1
Uncharacterized protein (207 aa)
           
  0.835
MLOC_12057.1
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner (217 aa)
   
   
  0.786
MLOC_36722.6
Uncharacterized protein; Belongs to the argonaute family (633 aa)
     
   
  0.757
MLOC_53845.1
Uncharacterized protein (646 aa)
           
  0.745
MLOC_12166.1
Uncharacterized protein (322 aa)
           
  0.745
MLOC_65646.3
Uncharacterized protein (612 aa)
           
  0.708
MLOC_24191.1
Uncharacterized protein (234 aa)
           
  0.705
MLOC_54359.2
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (894 aa)
           
  0.685
Your Current Organism:
Hordeum vulgare
NCBI taxonomy Id: 4513
Other names: H. vulgare, Hordeum vulgare, Hordeum vulgare L., barley
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