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MLOC_51152.1 protein (Hordeum vulgare) - STRING interaction network
"MLOC_51152.1" - Cytoplasmic tRNA 2-thiolation protein 2 in Hordeum vulgare
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MLOC_51152.1Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (496 aa)    
Predicted Functional Partners:
CTU1
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (359 aa)
     
  0.999
MLOC_63700.1
Uncharacterized protein (399 aa)
     
  0.983
MLOC_33537.1
Uncharacterized protein (604 aa)
     
  0.983
CNX5
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide t [...] (471 aa)
     
 
  0.926
MLOC_64815.2
Uncharacterized protein (649 aa)
     
  0.910
MLOC_19079.1
Predicted protein (293 aa)
     
        0.865
MLOC_69818.1
Uncharacterized protein (360 aa)
     
        0.863
MLOC_62438.1
Uncharacterized protein (327 aa)
     
        0.863
MLOC_58868.1
Uncharacterized protein (443 aa)
     
        0.837
MLOC_10314.1
Uncharacterized protein; Belongs to the MCM family (505 aa)
     
   
  0.826
Your Current Organism:
Hordeum vulgare
NCBI taxonomy Id: 4513
Other names: H. vulgare, Hordeum vulgare, Hordeum vulgare L., barley
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