STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCAP_01887S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (307 aa)    
Predicted Functional Partners:
TCAP_05420
Adenine phosphoribosyltransferase.
 
 
 0.988
TCAP_01815
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
  
 
 0.950
MRI1
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
 
 0.926
TCAP_06525
Dihydroorotate dehydrogenase (Quinone), mitochondrial.
   
 
 0.881
TCAP_07469
Acyl-CoA dehydrogenase family member 10.
  
 
 0.879
TCAP_02159
Bifunctional epoxide hydrolase 2.
  
 
 0.879
TCAP_05529
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 
 0.878
TCAP_06111
Nicotinate phosphoribosyltransferase.
    
 0.840
TCAP_00261
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
    
 0.826
TCAP_01137
Xanthine dehydrogenase.
   
 
 0.821
Your Current Organism:
Tolypocladium capitatum
NCBI taxonomy Id: 45235
Other names: Clavaria capitata, Cordyceps capitata, Elaphocordyceps capitata, T. capitatum, Tolypocladium capitatum (Holmsk. : Fr.) Quandt, Kepler & Spatafora, 2014, Torrubia capitata
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