STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxDHypothetical protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (338 aa)    
Predicted Functional Partners:
lpxC
Hypothetical protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
 0.999
Aasi_0288
Hypothetical protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
0.989
Aasi_0753
Hypothetical protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
 
 0.987
lpxK
Hypothetical protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.861
Aasi_0480
Hypothetical protein; PROFILE: PS51186, GCN5-related N-acetyltransferase; PFAM: PF00583, GCN5-related N-acetyltransferase; SUPERFAMILY: SSF55729, Acyl-CoA N-acyltransferase; GENE3D: G3DSA:3.40.630.30, Acyl-CoA N-acyltransferase.
 
   
 0.844
rpsB
Ribosomal protein S2; PROSITE: PS00435, Haem peroxidase, plant/fungal/bacterial; PROFILE: PS50929, ABC transporter, transmembrane region, type 1;PS50893, ABC transporter-like; SUPERFAMILY: SSF90123, ABC transporter, transmembrane region, type 1; PFAM: PF00664, ABC transporter, transmembrane region;PF00005, ABC transporter-like; PRODOM: PD000006, ABC transporter-like; SMART: SM00382, AAA+ ATPase, core; Belongs to the universal ribosomal protein uS2 family.
 
  
 0.775
accA
Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
    0.762
acpP
Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.730
Aasi_0783
Hypothetical protein; PFAM: PF00560, Leucine-rich repeat; SMART: SM00368, Leucine-rich repeat, ribonuclease inhibitor subtype.
  
    0.723
Aasi_1160
Hypothetical protein; PROSITE: PS01150, NADH dehydrogenase (ubiquinone), 20 kDa subunit; PANTHER: PTHR11995:SF2, NADH dehydrogenase (ubiquinone), 20 kDa subunit;PTHR11995, [NiFe]-hydrogenase-3-type complex, small subunit/NADH:quinone oxidoreductase, subunit NuoB; PFAM: PF01058, NADH ubiquinone oxidoreductase, 20 kDa subunit; TIGRFAMS: TIGR01957, NADH dehydrogenase (ubiquinone), 20 kDa subunit.
  
 
 0.635
Your Current Organism:
Amoebophilus asiaticus
NCBI taxonomy Id: 452471
Other names: C. Amoebophilus asiaticus 5a2, Candidatus Amoebophilus asiaticus 5a2, Candidatus Amoebophilus asiaticus str. 5a2, Candidatus Amoebophilus asiaticus strain 5a2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.