STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
recAHypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (354 aa)    
Predicted Functional Partners:
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.999
topA
Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
  
 0.961
recX
Hypothetical protein; Modulates RecA activity; Belongs to the RecX family.
  
 
 0.952
Aasi_0301
Hypothetical protein; PFAM: PF07977, Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ;PF03331, UDP-3-O-acyl N-acetylglucosamine deacetylase; PRODOM: PD011499, UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal; GENE3D: G3DSA:3.30.230.20, UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal;G3DSA:3.30.1700.10, UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal; TIGRFAMS: TIGR01750, Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ;TIGR00325, UDP-3-O-acyl N-acetylglucosamine deacetylase; Belongs to the CinA family.
 
  
 0.935
Aasi_1160
Hypothetical protein; PROSITE: PS01150, NADH dehydrogenase (ubiquinone), 20 kDa subunit; PANTHER: PTHR11995:SF2, NADH dehydrogenase (ubiquinone), 20 kDa subunit;PTHR11995, [NiFe]-hydrogenase-3-type complex, small subunit/NADH:quinone oxidoreductase, subunit NuoB; PFAM: PF01058, NADH ubiquinone oxidoreductase, 20 kDa subunit; TIGRFAMS: TIGR01957, NADH dehydrogenase (ubiquinone), 20 kDa subunit.
  
 
 0.927
Aasi_0038
UvrD/REP helicase; PANTHER: PTHR21090:SF4, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: PF00275, 3-phosphoshikimate 1-carboxyvinyltransferase, core; SUPERFAMILY: SSF55205, RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta; PRODOM: PD001867, 3-phosphoshikimate 1-carboxyvinyltransferase, core; GENE3D: G3DSA:3.65.10.10, 3-phosphoshikimate 1-carboxyvinyltransferase, core; TIGRFAMS: TIGR01072, UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
  
 
 0.893
Aasi_0152
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.880
Aasi_0286
Hypothetical protein; PROSITE: PS00096, Glycine hydroxymethyltransferase; PANTHER: PTHR11680, Glycine hydroxymethyltransferase; SUPERFAMILY: SSF53383, Pyridoxal phosphate-dependent transferase, major region; PFAM: PF00464, Glycine hydroxymethyltransferase; PIR: PIRSF000412, Glycine hydroxymethyltransferase; GENE3D: G3DSA:3.40.640.10, Pyridoxal phosphate-dependent transferase, major region, subdomain 1.
  
  
 0.879
Aasi_1325
Hypothetical protein; PFAM: PF01609, Transposase, IS4-like.
  
 
 0.850
Aasi_0999
Hypothetical protein; PFAM: PF01609, Transposase, IS4-like.
  
 
 0.811
Your Current Organism:
Amoebophilus asiaticus
NCBI taxonomy Id: 452471
Other names: C. Amoebophilus asiaticus 5a2, Candidatus Amoebophilus asiaticus 5a2, Candidatus Amoebophilus asiaticus str. 5a2, Candidatus Amoebophilus asiaticus strain 5a2
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