STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Oter_41902-oxoglutarate dehydrogenase, E1 subunit; KEGG: gsu:GSU2449 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region. (920 aa)    
Predicted Functional Partners:
Oter_4191
2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
Oter_4192
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: bbt:BBta_0398 dihydrolipoamide dehydrogenase.
 
 0.995
Oter_2845
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.990
Oter_2712
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: chu:CHU_1086 dihydrolipoyl dehydrogenase (dihydrolipoamide dehydrogenase).
 
 0.989
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.989
Oter_0050
PFAM: biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: bte:BTH_I1865 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase.
 
 0.987
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.963
Oter_3132
Isocitrate dehydrogenase, NADP-dependent; KEGG: mag:amb0607 monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family.
   
 
 0.921
Oter_0670
KEGG: cau:Caur_1881 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 0.912
Oter_0669
PFAM: ferredoxin; KEGG: lic:LIC12003 succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
 
 
 0.905
Your Current Organism:
Opitutus terrae
NCBI taxonomy Id: 452637
Other names: O. terrae PB90-1, Opitutus terrae DSM 11246, Opitutus terrae PB90-1, Verrucomicrobiales PB90-1, Verrucomicrobiales str. PB90-1
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