STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnec_01332-alkenal reductase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: pnu:Pnuc_0123 peptidase S1 and S6, chymotrypsin/Hap; Belongs to the peptidase S1C family. (392 aa)    
Predicted Functional Partners:
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.720
Pnec_1611
Sodium/hydrogen exchanger; PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: pnu:Pnuc_1906 potassium efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.606
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
  0.585
Pnec_0136
Cytochrome b/b6 domain; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
 0.583
Pnec_0718
KEGG: pnu:Pnuc_1165 diguanylate cyclase.
  
  
 0.578
Pnec_0135
Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
   0.543
Pnec_1522
Response regulator receiver protein; KEGG: pnu:Pnuc_1809 histidine kinase.
  
  
 0.543
Pnec_0947
PFAM: FAD dependent oxidoreductase; KEGG: pnu:Pnuc_0895 FAD dependent oxidoreductase.
   
 
  0.484
Pnec_0141
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bxe:Bxe_A3016 putative TPR/sulfotransferase domain protein, FlbA-like.
   
 0.472
Pnec_1228
PFAM: Malonyl-CoA decarboxylase; KEGG: pnu:Pnuc_0627 malonyl-CoA decarboxylase.
   
 
  0.465
Your Current Organism:
Polynucleobacter necessarius
NCBI taxonomy Id: 452638
Other names: P. necessarius STIR1, Polynucleobacter necessarius STIR1, Polynucleobacter necessarius subsp. necessarius STIR1
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