node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnec_0225 | Pnec_1511 | Pnec_0225 | Pnec_1511 | PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0207 PfkB domain protein. | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.936 |
Pnec_0225 | Pnec_1606 | Pnec_0225 | Pnec_1606 | PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0207 PfkB domain protein. | 5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase. | 0.900 |
Pnec_0225 | adk | Pnec_0225 | Pnec_0309 | PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0207 PfkB domain protein. | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.930 |
Pnec_0225 | apt | Pnec_0225 | Pnec_0968 | PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0207 PfkB domain protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.950 |
Pnec_0225 | guaA | Pnec_0225 | Pnec_0530 | PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0207 PfkB domain protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.609 |
Pnec_1511 | Pnec_0225 | Pnec_1511 | Pnec_0225 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0207 PfkB domain protein. | 0.936 |
Pnec_1511 | Pnec_1606 | Pnec_1511 | Pnec_1606 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase. | 0.900 |
Pnec_1511 | adk | Pnec_1511 | Pnec_0309 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.941 |
Pnec_1511 | apt | Pnec_1511 | Pnec_0968 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.954 |
Pnec_1511 | guaA | Pnec_1511 | Pnec_0530 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.864 |
Pnec_1511 | hisF | Pnec_1511 | Pnec_0111 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.807 |
Pnec_1511 | hisH | Pnec_1511 | Pnec_0109 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.809 |
Pnec_1511 | purH | Pnec_1511 | Pnec_1581 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: pnu:Pnuc_1877 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.992 |
Pnec_1511 | purL | Pnec_1511 | Pnec_0902 | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
Pnec_1606 | Pnec_0225 | Pnec_1606 | Pnec_0225 | 5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase. | PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0207 PfkB domain protein. | 0.900 |
Pnec_1606 | Pnec_1511 | Pnec_1606 | Pnec_1511 | 5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase. | KEGG: pnu:Pnuc_1794 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.900 |
Pnec_1606 | adk | Pnec_1606 | Pnec_0309 | 5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase. | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.900 |
Pnec_1606 | apt | Pnec_1606 | Pnec_0968 | 5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
Pnec_1606 | gmk | Pnec_1606 | Pnec_0793 | 5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
Pnec_1606 | guaA | Pnec_1606 | Pnec_0530 | 5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.900 |