STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
acsAPutative acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)    
Predicted Functional Partners:
ackA
Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.979
citA1
Putative citrate synthase; Belongs to the citrate synthase family.
  
 0.972
citA2
Putative citrate synthase; Belongs to the citrate synthase family.
  
 0.958
pta
Putative phosphate acetyltransferase; Protein synonym:phosphotransacetylase.
  
 
 0.955
aceB
Putative malate synthase; Belongs to the malate synthase family.
   
 0.955
adhE
Putative aldehyde dehydrogenase/alcohol dehydrogenase; Bifunctional protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.950
KSE_45310
Putative 2-oxoglutarate ferredoxin oxidoreductase alpha subunit.
  
 
 0.949
KSE_07740
Putative acetyl-CoA acetyltransferase; Protein synonym:acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.935
KSE_18900
Putative fatty acid oxidation complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.935
KSE_47240
Putative acetyl-CoA acetyltransferase; Protein synonym:acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.935
Your Current Organism:
Kitasatospora setae
NCBI taxonomy Id: 452652
Other names: K. setae KM-6054, Kitasatospora setae KM-6054, Kitasatospora setae str. KM-6054, Kitasatospora setae strain KM-6054
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