STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPutative phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (931 aa)    
Predicted Functional Partners:
pckG
Putative GTP-dependent phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.961
pyk1
Putative pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.940
pyk2
Putative pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.940
citA1
Putative citrate synthase; Belongs to the citrate synthase family.
     
 0.940
eno
Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.939
mdh
Putative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 
 0.938
ppdk
Protein synonym:pyruvate, orthophosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.928
gltB
Putative glutamate synthase large subunit.
  
  
 0.907
citA2
Putative citrate synthase; Belongs to the citrate synthase family.
     
 0.899
aceB
Putative malate synthase; Belongs to the malate synthase family.
     
 0.857
Your Current Organism:
Kitasatospora setae
NCBI taxonomy Id: 452652
Other names: K. setae KM-6054, Kitasatospora setae KM-6054, Kitasatospora setae str. KM-6054, Kitasatospora setae strain KM-6054
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