STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Achl_1787TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; KEGG: art:Arth_2031 hypothetical protein. (340 aa)    
Predicted Functional Partners:
Achl_3859
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: art:Arth_4083 ATP-dependent DNA ligase.
   
 0.984
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.880
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.749
Achl_1786
PFAM: dienelactone hydrolase; KEGG: art:Arth_2029 dienelactone hydrolase.
 
     0.672
Achl_1774
PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aau:AAur_2033 putative 5'-3' exonuclease.
  
   
 0.539
Achl_0614
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: art:Arth_0395 hypothetical protein.
 
   
 0.514
Achl_3874
KEGG: art:Arth_4100 hypothetical protein.
  
     0.490
Achl_1540
PFAM: Formamidopyrimidine-DNA glycosylase catalytic domain protein; DNA glycosylase/AP lyase, H2TH DNA-binding; KEGG: art:Arth_1539 DNA-formamidopyrimidine glycosylase; Belongs to the FPG family.
 
     0.478
Your Current Organism:
Pseudarthrobacter chlorophenolicus
NCBI taxonomy Id: 452863
Other names: Arthrobacter chlorophenolicus A6, P. chlorophenolicus A6, Pseudarthrobacter chlorophenolicus A6
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